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J Multidiscip Healthc. 2009; 2: 53–59
Tara Sampalli,1 Elizabeth Berlasso,1 Roy Fox,1 and Mark Petter
The objective of this study was to examine the effect of a mindfulness-based stress reduction (MBSR) program on women diagnosed with conditions such as multiple chemical sensitivity (MCS), chronic fatigue syndrome (CFS), and fibromyalgia (FM).
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Environ Health. 2007; 6: 6
Eckart Schnakenberg, Karl-Rainer Fabig, Martin Stanulla, Nils Strobl, Michael Lustig, Nathalie Fabig, and Werner Schloot
This study concluded that individuals with self-reported chemical-related sensitivity were more frequent carriers of genetic variants of GSTM1, GSTT1 and NAT2. The authors believe that the results reflect the gene-environment associations of increased chemical-related sensitivity in individuals suffering from diseases like MCS, IEI or CFS but have to be reproduced in further studies to prove the observations.
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Environ Health Perspect. 2003 Sep;111(12):1490-7
Caress SM,Steinemann AC
In this review the findings of a two-phase study of the prevalence, symptomatology(set of symptoms), and etiology(cause) of multiple chemical sensitivities (MCS) are summarised. The possible triggers are explored, the potential linkage between MCS and other disorders, and the lifestyle alterations produced by MCS
The findings suggest that MCS has a physiological and not a psychological cause
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Feb 2014
Dandoft TM, Elberling J,Brix S, Szecsi PB, Vesterhauge S, Skovbjerg S
Objective:Blood of 148 healthy controls were compared with 150 MCS un-exposed individuals to compare plasma levels of cytokines( these are cell signalling proteins that are especially important in the immune system when fighting infections).
Conclusion: MCS individuals have an increase in certain cytokines compared to healthy individuals. These cytokines can pick up foreign bodies and are key in helping fight infection.
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Allergy Asthma Immunol Res. 2014 Sep;6(5):409-14. Epub 2014 Mar 21.
This study evaluated the prevalence and related factors of MCS targeting Korean adults using the Quick Environmental Exposure and Sensitivity Inventory (QEESI©).
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Dec 3rd 2013
Pigatto PD, Minoia C, Ronchi A, Brambilla L, Passoni M, Somalvico F, Bombeccari GP, Guzzi G
A retrospective review of medical records of 41 patients with MCS looking at prevalence of allergy to metals and toxicological aspects. In conclusion there was an increase in prevalence of metal allergy and elevation of mercury levels in bio indicators among the patients.
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Contact Dermatitis. 2014 May;70(5):276-81. doi: 10.1111/cod.12171.
Mann J, McFadden JP, White JM, White IR, Banerjee P.
This study investigates the frequencies of positive test reactions to 26 fragrance substances for which labelling is mandatory in the EU.
The findings confirm that the standard fragrance markers fail to identify patients with contact allergies to the 26 fragrances.
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November 21, 2013
Kenichi Azuma,Iwao Uchiyama,Hirohisa Takano,Mari Tanigawa,Michiyo Azuma,Ikuko Bamba,Toshikazu Yoshikaw
MCS patients apparently process odors differently from controls. This may be due to activation in the prefrontal cortex(PFC) of the brain.
These changes were studied by infrared imagery looking at cerebral blood flow, using an odor stimulation test. 12 MCS patients vs 11 controls. There were significant changes in activity in the left and right sides of the PFC compared to changes in the central region in the controls.
Despite the small sample size,these results suggest that prefrontal information processing in the brain associated with odor processing plays a significant role in this disorder. In other words the odor processing region of the brain is slightly different in MCS patients compared to controls.
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A Disability&Society,Volume24,No.2,March2009,187-199
Pamela Reed Gibson
This paper looks at how chemical and electric exposures can act as disability barriers to those who develop intolerance to them.
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Air Quality, Atmosphere and Health, 2011
Anne C. Steinemann, Lisa G. Gallagher, Amy L. Davis, Ian C. MacGregor
Common laundry products, used in washing and drying machines, can contribute to outdoor emissions through dryer vents. The types and amounts of chemicals emitted are largely unknown. This study looked at the volatile organic compounds (VOCs) both fragranced laundry products and in the air emitted from dryer vents during use of these products.
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November 13 2010
Katerndahl D.A., Bell I.R., Palmer R.F., Miller C.S.
Psychiatric comorbidities contribute to functional limitations and increased health care use. Chemical intolerance offers an explanation. Symptoms may resolve or improve with the avoidance of salient chemical, dietary (including caffeine and alcohol), and drug triggers.
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J Environ Public Health 2012: 304314
Sine Skovbjerg, Nikolaj Drimer Berg,Jesper Elberling and Karl Bang Christensen
To evaluate a Danish translation of the Quick Environmental Exposure and Sensitivity Inventory- QEESI ( a test which helps researchers, doctors, and their patients identify individuals with multiple chemical intolerances).
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Aug 10 2012
Pichery C, Bellanger M, Zmirou-Navier D et al
These results emphasize that efforts to reduce MeHg exposures would have high social benefits by preventing the serious and lifelong consequences of neurodevelopmental deficits in children.
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2012
triWang F, Li C, Liu W, Jin Y.
Findings suggest that Nitric Oxide (NO) signalling pathways may induce airway inflammation in short term VOC exposure in mice and the airway inflammatory response may be modulated by neurological signalling.
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Paper presented at the Chemical Injury information network conference Fairfax Oct 3-5th 2003
Pamela R Gibson, James Madison University
This US study looked at the workplace accommodation that MCS sufferers are provided with and whether they are helpful in maintaining employment.
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Environmental Impact Assessment Review Volume 31, Issue 3, April 2011, 328–333
Anne C. Steinemann, Ian C. MacGregor,Sydney M. Gordon,Lisa G. Gallagher,Amy L. Davis,Daniel S. Ribeiro,Lance A. Wallace
This study investigated the volatile organic compounds(VOCs) emitted from 25 common fragranced consumer products—laundry products, personal care products, cleaning supplies, and air fresheners in the US. Relatively little is known about the composition of these products, due to lack of prior study, complexity of formulations, and limitations and protections on ingredient disclosure in the U.S.
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Scand J Prim Health Care. 2009;27(3):148-52. doi: 10.1080/02813430902888355.
Skovbjerg S, Johansen JD, Rasmussen A, Thorsen H, Elberling J.
A nationwide cross-sectional postal questionnaire survey to describe general practitioners' (GPs') evaluation of and management strategies in relation to patients who seek medical advice because of multiple chemical sensitivity (MCS) in Denmark.
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International Journal of Hygiene and Environmental Health, Volume 213, Issue 2, March 2010, Pages 131–139
Nikolaj Drimer Berg, Henrik Berg Rasmussen, Allan Linneberg,Charlotte Brasch-AndersenMogens Fenger,Asger Dirksen,Søren Vesterhauge, Thomas Werge, Jesper Elberling
The purpose of this study was to look at genetic susceptibility factors for MCS. Ninety six MCS patients and 1,207 controls from a general population divided into four severity groups of chemical sensitivity were genotyped for variants in certain genes.
The results suggest that variants in the genes examined are of less importance to MCS than previously reported.
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May 24 2012
Moss J.I.
Gulf War illnesses (GWI) share many of the features of chronic fatigue syndrome (CFS) and both CFS and GWI may be the result of chronic immune system processes.
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Kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho Hokoku. 2007;(125):72-8
Jinno H, Tanaka-Kagawa T,Obama T, Miyagawa M, Yoshikawa J, Komatsu K, Tokunaga H.
In this study, the emission rate of volatile organic compounds(VOCs) and carbonyl compounds for 30 air fresheners and deodorizers by the standard small chamber test method (JIS A 1901) were investigated.
